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The page below is a sample from the LabCE course Biochemical Markers of Osteoporosis. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Type 2

Type 2 occurs in women or men older than 70 years of age and usually is associated with decreased bone formation along with decreased ability of the kidney to produce 1,25(OH)2D3. The vitamin D deficiency results in decreased calcium absorption, which increases the PTH level and therefore bone resorption. In type 2 osteoporosis, cortical (outer surface of the bone) and trabecular (spongy) bone is lost, leading to increased risk of hip, long bone, and vertebral fractures.