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The page below is a sample from the LabCE course Antiplatelet Medication Response Testing: Aspirin and Clopidogrel. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Clopidogrel Response Analysis: Whole Blood Impedance Aggregometry

Whole blood methods that detected platelet aggregation using electrical impedance technology can also be utilized for clopidogrel response testing. In one method, ADP is used as the agonist, typically at a concentration of 5-20 µmol/L. If a patient's test result shows a low response (ADP-induced impedance exceeding 5 Ω (ohms)), it could indicate clopidogrel non-responsiveness.