Neuroendocrine and Neurotransmitter Effects

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Neuroendocrine and Neurotransmitter Effects

Neurotransmitters are chemical messengers that carry a signal between nerve cells and impart an effect when they bind to specific receptors on cells.

As previously shown, the hypothalamic hormone Prolactin inhibiting factor (PIF) was later discovered to be the neurotransmitter Dopamine. Other neurotransmitters that effect secretion of anterior lobe pituitary hormones are summarized in the table.
Table 2: Neurotransmitter Effect on Pituitary Hormonal Secretion
Pituitary HormonesStimulated byInhibited by
FSH
LH		Gamma-Aminobutyric Acid (GABA)
Acetylcholine
Norepinephrine 		Serotonin
Dopamine
Endorphins
PRLEndorphins
Norepinephrine 		Dopamine
GHDopamine
Serotonin
Endorphins
Norepinephrine
TSHNorepinephrine Dopamine
Serotonin
Endorphins
ACTHEndorphins
Serotonin
Acetylcholine 		GABA