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The page below is a sample from the LabCE course Pituitary Hormones. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Neuroendocrine and Neurotransmitter Effects

Neurotransmitters are chemical messengers that carry a signal between nerve cells and impart an effect when they bind to specific receptors on cells.

As previously shown, the hypothalamic hormone Prolactin inhibiting factor (PIF) was later discovered to be the neurotransmitter Dopamine. Other neurotransmitters that effect secretion of anterior lobe pituitary hormones are summarized in the table.
Neurotransmitter Effect on Pituitary Hormonal Secretion
Pituitary Hormones
Stimulated by
Inhibited by
FSH
LH
Gamma-Aminobutyric Acid (GABA)
Acetylcholine
Norepinephrine
Serotonin
Dopamine
Endorphins
PRL
Endorphins
Norepinephrine
Dopamine
GH
Dopamine
Serotonin
Endorphins
Norepinephrine
TSH
Norepinephrine
Dopamine
Serotonin
Endorphins
ACTH
Endorphins
Serotonin
Acetylcholine
GABA