The table below lists the reaction types that were previously described and summarizes additional testing that may be ordered.
Anaphylactoid and anaphylactic
|
- Anti-IgA
- IgA quantitative
|
Febrile nonhemolytic |
- If initial testing is negative, perform a culture to rule out a bacterially-contaminated blood component
- When other sources of the fever have been ruled out, the reaction is categorized as a febrile nonhemolytic transfusion reaction (FNHTR).
|
Hemolytic
|
- Bilirubin
- Haptoglobin
- Lactate dehydrogenase (LDH)
|
Transfusion-associated bacterial sepsis
|
- Gram stain
- Culture of component
- Blood culture of recipient
|
Transfusion-associated circulatory overload (TACO)
|
- Chest x-ray
- B-type natriuretic peptide (BNP)
|
Transfusion-related acute lung injury (TRALI)
|
- Chest x-ray
- BNP
- Leukocyte antibody screens (donor and recipient plasma)
- Antigen typing of recipient
|