Heartland Virus

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The page below is a sample from the LabCE course Tickborne Diseases. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Tickborne Diseases (online CE course)
Heartland Virus

The Heartland virus is a phlebovirus in the family Bunyaviridae. As of January 2021, 50 cases of Heartland virus disease have been reported in the Midwestern and Southern United States. They became ill between May and September. A few cases were fatal in patients with comorbidities. The virus has been found in the Lone Star tick (Amblyomma americanum), but it is not known whether this tick can transmit the virus to humans through a bite.
Symptoms are typical of other tickborne diseases:
  • Fever
  • Fatigue
  • Headache
  • Muscle ache
  • Loss of appetite
  • Nausea
There is no treatment, and testing is currently available through the CDC. Blood samples of 1,428 deer, raccoon, coyotes, and moose collected from killed animals revealed 103 seropositive animals in the geographic areas of Heartland virus disease.
44. “Statistics & Maps.” Centers for Disease Control and Prevention, 23 Apr. 2021, https://www.cdc.gov/heartland-virus/statistics/index.html.

Cases of Heartland virus disease by January 2021 (44).