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The page below is a sample from the LabCE course Hemoglobinopathies: Hemoglobin S Disorders. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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CBC and RBC Morphology

CBC results for patients with double heterozygous condition of sickle cell with beta thalassemia (Hb S/Bthal) can be asymptomatic or demonstrate a slight to moderate anemia. The CBC and peripheral blood smear for a patient with Hb S/Bthal, which appear below, reflect results more consistent with thalassemia than hemoglobinopathy. The hemoglobin electrophoresis results on the following page revealed this condition.

Reference intervals may vary between facilities and are dependent on patient age and gender. The reference intervals that are shown below are specific to this case.
Patient Result
Reference Interval
White blood cell count (WBC)11.44.0 - 11.0 x 109/L
Red blood cell count (RBC)6.374.5 - 5.9 x 1012/L
13.613.8 - 17.2 g/dL
Hematocrit38.141 - 53%
MCV59.980 - 100 fL
RDW18.912 - 14.6
Platelet count150 - 440 x 109/L