The page below is a sample from the LabCE course Hemoglobinopathies: Hemoglobin S Disorders. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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CBC Results and RBC Morphology

A patient with sickle cell trait is asymptomatic except under extreme hypoxic conditions. CBC results for patients with sickle cell trait (Hb SA) can be near normal or reflect a slight anemia (as shown in this case). A typical automated CBC report and peripheral blood smear for an asymptomatic adult male patient with Hb SA appears below. Reference intervals may vary between facilities and are dependent on patient age and gender. The reference intervals that are shown below are specific to this case.
Parameter
Patient Result
Reference Interval
White blood cell count (WBC)5.33.8 - 9.8 x 109/L
Red blood cell count (RBC)4.784.50 - 4.70 x 1012/L
Hemoglobin
12.913.8 - 17.2 g/dL
Hematocrit39.740 - 50%
MCV8383 - 101 fL
RDW14.211 - 14.5
Platelet count250140 - 440 x 109/L