Home Products Most Popular Contact
No items in your cart.
The page below is a sample from the LabCE course Hemoglobinopathies: Hemoglobin S Disorders. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Hemoglobinopathies: Hemoglobin S Disorders (online CE course) »
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 106 CE courses, most popular
$95 Add to cart
Pick Your Courses
Up to 8 CE hours
$50 Add to cart
Individual course$20 Add to cart

Sickle Cell Disorder Frequency: Hb S / Thalassemia

Hb S / thalassemia combinationAffected populationsSeverityComments
Hb S beta thalassemia
North Africa, India, and the Mediterranean region, especially Greece and Turkey.
Hb S beta-plus thalassemia, type 1 and Hb S beta-minus thalassemia need supportive therapy and may have severe anemia
Hb S beta-plus thalassemia, type 2 requires very little medical attention
Hb SA alpha-plus thalassemia
Common in persons of African ancestry
Usually asymptomatic
Less hemoglobin S produced than in persons with Hb S trait
Hb SS-alpha thalassemia (either plus or zero)African and Mediterranean ancestryMild anemia midway in severity between sickle cell disease and trait
Produce increased levels of Hb F in proportion to the number of alpha gene deletions present. This acts to retard the sickling process.