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The page below is a sample from the LabCE course Bioterrorism: The Laboratory's Role and Response. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Agent: Smallpox (Virus)

Most likely means of dissemination: As an aerosol

Primary route of entry: Inhalation

General signs and symptoms: High fever, extreme lethargy, severe headache, severe backache, severe abdominal pain, with a rash that starts as red bumps but quickly develops into small, itchy blisters.

Photo courtesy of the CDC archives.