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Case 5 More History
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Parasitology Case Studies: Protozoa in Blood (by ASCLS)
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Case 5 More History
Patient had taken 5 trips to Mexico from 1970-1998 but all were less than 2 weeks in tourist hotels
Her only symptom was fatigue
She had not used IV drugs or had either a blood transfusion or organ transplant
The patient was not the daughter of Latin American immigrants
She had resided on 8 forested acres near New Orleans for 29 years
Her home was infected with
Triatoma sanquisuga
and when the dead bugs were tested by PCR, they were positive for
Trypanosoma cruzi
Armadillo population known to carry the trypanosomes was increased on her property
Her night gown was smeared with blood and feces from the bugs
4 weeks after being bitten she was positive for antibodies to
T. cruzi
by indirect immunofluorescence (titer 1:128)
Hemoculture in macrophages was positive in blood drawn 4 months after being bitten
The trypanosomes were confirmed as
T. cruzi
by molecular amplification of a specific 24S
a
rRNA target
Patient decided against treatment
CDC/ Dr. A.J. Sulzer
Cell culture of
T. cruzi
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