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The page below is a sample from the LabCE course Fundamentals of Hemostasis. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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The Fibrinolytic System

  • There is a very close relationship between the formation of fibrin, and its eventual degradation, or lysis.
  • A fibrin clot serves as a temporary seal, intended to prevent continued blood loss from the damaged vessel while repair activities are performed.
  • The breakdown of the clot begins almost as soon as the clot is formed!
  • The process by which fibrin is broken down and removed from the clot, ultimately leading to complete dissolution of the clot, is called fibrinolysis.