Home Products Most Popular Contact
No items in your cart.
The page below is a sample from the LabCE course Fundamentals of Hemostasis. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Fundamentals of Hemostasis (online CE course) »
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 111 CE courses, most popular
$95 Add to cart
Pick Your Courses
Up to 8 CE hours
$50 Add to cart
Individual course$20 Add to cart

Secondary Hemostasis – The Extrinsic Pathway

  • The shortest, and least complex of the three pathways, the extrinsic pathway primarily focuses on the interaction of tissue factor with factor VII, leading to the activation of factor VII.
  • Tissue factor, a substance expressed on the surface of cells such as fibroblasts and macrophages found outside the vasculature, initiates coagulation when plasma contained within the vessel walls leaks outside the broken vessel, and comes into contact with these cells.
  • The nomenclature, extrinsic pathway, comes from the fact that tissue factor is external to the vasculature.