Continuing Education Courses
Continuing Education for MLS & MLT
Continuing Education for Phlebotomists
Continuing Education for Histologists
HR Courses
Intro to the Medical Lab
Video Continuing Education Courses
All Available Courses
Exam Simulators
Exam Simulator for MLS & MLT
NSH + LabCE Histology Exam Simulator
Phlebotomy Exam Simulator
Molecular Exam Simulator
Case Simulators
RBC Morphology Simulator
White Blood Cell Differential Case Simulator
Advanced WBC Differential Case Simulator
Urinalysis Case Simulator
Body Fluid Case Simulator
Bacteriology Case Simulator
Blood Culture Gram Stain Case Simulator
LabCE Quiz Game
Contact & Support
Log In
Log In
Primary Hemostasis – The Vascular System & Platelet Involvement
This version of the course is no longer available.
Need multiple seats for your university or lab?
Get a quote
The page below is a sample from the LabCE course
. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.
Learn more about (online CE course)
Primary Hemostasis – The Vascular System & Platelet Involvement
As discussed earlier, a break in the vessel endothelium leads to exposure of collagen and the vessel's subendothelial surface.
Ruptured endothelial cells leak
ADP
and
Serotonin
, which are the chemical triggers that induce platelet adhesion, the next step in the sequence of hemostatic events.
Circulating platelets are drawn to the area by those liberated chemical signals, and begin to physically attach themselves to the rough, damaged surfaces of the breach.
As platelets continue to arrive and bind to the exposed collagen and basement membrane, a rudimentary barrier begins to form, as the platelets themselves serve to fill in the breached vessel wall.
Platelets possess an inherent “sticky” property which enables them to adhere to one another, and not just to the damaged vessel endothelium.
The process by which platelets bind to one another is referred to as
platelet aggregation
, and is vital because it allows for a
platelet plug
to be formed.
The platelet plug is the structure responsible for plugging the hole in the vessel wall.
X
×