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The page below is a sample from the LabCE course Tumor Markers. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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CA 549

CA 549 is also a marker for breast and ovarian carcinoma.
  • CA 549 lacks the sensitivity and specificity to serve as an effective screening tool.
  • CA 549 is also elevated in some pregnancies, in benign breast disease, and in liver disease.
  • Some ovarian, lung, and even prostate cancers may elevate CA 549 levels.
  • Similar to CA 15-3, CA 549 has limited utility in detecting early breast carcinoma, due to the low prevalence of individuals with elevated CA 549 during the early stages of breast cancer.9
  • CA 549 has strong utility as an indicator of recurrence of breast cancer after previous successful treatment to reduce tumor growth.
  • An increasing level of CA 549 after previous successful attempts to decrease or stabilize tumor growth parallels the redevelopment or increasing growth of a breast carcinoma.9