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The page below is a sample from the LabCE course Tumor Markers. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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The Ideal Tumor Marker Would be Adaptable to Laboratory Analysis

Ideally, the substance produced by the cancer cells would contain identical antigenic markers in every individual where active cells are found. The purified substance would be isolated and well-characterized to permit the development of analytical methods, such as those employing immunoassay principles in which antibodies may be developed specific to epitopes or defined areas of the antigenic markers. Alternately, if purified forms of the tumor marker are amply stable to permit the preparation of calibration standards to facilitate accurate quantitation, chromatographic methods may be developed for the identification and measurement of the tumor marker in biological specimens.