The page below is a sample from the LabCE course Human Papillomavirus (HPV) and Molecular Testing for Cervical Cancer. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Low-Risk and High-Risk HPV Types

Low-risk HPV types are types: 6, 11, 42, 43, 44, 54, 61, 70, 72, and 81. These types can cause genital lesions but are considered non-carcinogenic types as they are not associated with cancerous lesions and are very rarely associated with precancerous lesions. HPV types 6 and 11 are the most common cause of genital condylomas (genital warts).

High-risk HPV types are types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73, and 82. Since these types are associated with cervical as well as other anogenital cancers, they are referred to as the carcinogenic or oncogenic HPV types. HPV types 16 and 18 are most commonly isolated in cervical cancer; however, infections with HPV type 16 or 18 do not always result in cancer.