The page below is a sample from the LabCE course Detecting and Evaluating Coagulation Inhibitors and Factor Deficiencies. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Interpreting the Mixing Study Results: Case Study One

A young patient is admitted from the emergency room with petechial bruising. The attending physician orders a battery of tests including a PT and aPTT. The laboratory performs the requested testing and the result of the aPTT is normal; however the PT is prolonged:

PT: 38 seconds (normal range 11-13 seconds)

aPTT: 32 seconds (normal range 21-34 seconds)

The physician then decides to order a mixing study for further analysis since the patient is not taking any oral anticoagulants, nor does she meet the known patient histories associated with prolonged PT results.