The page below is a sample from the LabCE course Detecting and Evaluating Coagulation Inhibitors and Factor Deficiencies. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Further Analyses for Factor Deficiencies (cont.)

A factor-deficient plasma is used for each factor that is suspected to be causing the prolongation. When the patient plasma is mixed with each of the specific factor-deficient plasmas, the factor that is deficient can be identified. If the aPTT or PT is still prolonged after mixing the patient sample with the specific factor-deficient plasma, this is most likely the factor that is deficient in the patient sample.