Home Products Most Popular Contact
No items in your cart.
The page below is a sample from the LabCE course Emerging Cardiovascular Risk Markers. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Emerging Cardiovascular Risk Markers (online CE course) »
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 106 CE courses, most popular
$95 Add to cart
Pick Your Courses
Up to 8 CE hours
$50 Add to cart
Individual course$20 Add to cart

LDL Phenotype by Electrophoresis

When LDL is resolved with electrophoresis, it reveals several subfractions. These subfractions are simply different size populations of LDL particles. Age, gender and lipid status can all affect the LDL subfractionation profile. Individuals who have less dense (also called "buoyant") LDL have most of their LDL in subfractions 1 and 2. These results are referred to as pattern or phenotype "A" and are normal.

Those with significant amounts of subfractions 3- 7 (more dense particles) are at higher cardiovascular risk. These patients have pattern or phenotype "B". The B pattern rarely occurs as an isolated disorder. It is usually accompanied by characteristics of the metabolic syndrome: hypertriglyceridemia, reduced HDL-C , abdominal obesity, insulin resistance, etc.