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The page below is a sample from the LabCE course Advances in Noninvasive Prenatal Testing For Down Syndrome and other Trisomies. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Abnormalities of chromosome number (Aneuploidy). Available at: http://www.utmb.edu/pedi_ed/CORE/MedicalGenetics/page_11.htm. Accessed January 28, 2016.

Aetna Clinical Coverage Policy, Serum Marker Screening for Down Syndrome, Policy #0464, reviewed 2/4/12. Available at: http://www.aetna.com/cpb/medical/data/400_499/0464.html. Accessed January 28, 2016.

AFP test information. American Pregnancy Organization. Available at: http://americanpregnancy.org/prenataltesting/afp.html. Accessed January 28, 2016.

American College of Obstetricians and Gynecologists. ACOG Committee Opinion No. 640, September 2015. Available at: http://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Genetics/Cell-free-DNA-Screening-for-Fetal-Aneuploidy. Accessed January 28, 2016.

Aneuploidy: NCBI, US Library of Medicine. Available at: http://www.ncbi.nlm.nih.gov/books/NBK21870/. Accessed January 29, 2016.

CAP Commission on Laboratory Accreditation- Laboratory Accreditation Program. Chemistry and Toxicology Checklist. Northfield, IL: College of American Pathologists: July 2015.

Definition of MSAFP (maternal serum alpha-fetoprotein. Available at: http://www.medterms.com/script/main/art.asp?articlekey=4446. Accessed January 29, 2016.

Down syndrome: Genetics home reference. US National Library of Medicine, NIH. Pub. 1/17/13. Available at: http://ghr.nlm.nih.gov/condition/down-syndrome. Accessed January 29, 2016.

Down syndrome. Mayo Clinic web site. Available at: http://www.mayoclinic.com/health/down-syndrome/DS00182. Accessed January 29, 2016.

Down Syndrome: The ARC, 2013 update. Available at: http://www.thearc.org/page.aspx?pid=2546. Accessed January 29, 2016.

Fetal Aneuploidy Detection by Maternal Plasma DNA Sequencing. California Technology Assessment Forum. [Draft]. Available athttp://www.ctaf.org/sites/default/files/u39/121017_draft_prenatal.pdf. Accessed January 29, 2016.

MPSS technical information. National Center for Biotechnology Information, NCBI. Available at: http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/TechMPSS.shtml. Accessed January 29, 2016.

Morris JK, Mutton DE, Alberman E. Revised estimates of the maternal age specific live birth prevalence of Down's syndrome. J Med Screen.2002;9(1):2–6.

Newberger DS. Down syndrome: Prenatal risk assessment and diagnosis. Available at: http://www.aafp.org/afp/2000/0815/p825.html. Accessed January 29, 2016.

Resta RG. Changing demographics of advanced maternal age (AMA) and the impact on the predicted incidence of Down syndrome in the United States: Implications for prenatal screening and genetic counseling. Am J Med Genet A. Feb 15 2005;133A(1):31–36.

Rodeck CH, Whittle MJ. Fetal Medicine: Basic Science and Clinical Practice. Philadelphia: Churchill Livingstone; 2009.

Second trimester maternal serum screening. AACC Lab tests online. Available at: : http://labtestsonline.org/understanding/analytes/triple-screen/tab/test. Accessed January 29, 2016. 

Sequencing-based trisomy testing for fetal aneuploidy. Cigna Medical Coverage Policy. http://www.cigna.com/assets/docs/health-care-professionals/coverage_positions/mm_0211_coveragepositioncriteria_down_syndrome_screening.pdf. Accessed January 29, 2016. 

Sietske NH, Perlstein D. Downs syndrome. Available at: http://www.medicinenet.com/down_syndrome/article.htm. Accessed January 29, 2016.

Test ID: MAFP. Mayo Clinic Website. Available at: http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/81169. Accessed January 29, 2016.

The Harmony Prenatal Test. Test information. Aiosa Diagnostics. Available at: http://www.ariosadx.com/about-the-science/. Accessed January 29, 2016.

Torres TT, Metta M, Ottenwälder B, Schlötterer C. Gene expression profiling by massively parallel sequencing. Genome Res. 2007 Nov 21 PMID: 18032722.

Tufts Health Plan provider policy. Genetic testing: Maternal tests for fetal trisomy. Available at: http://www.tuftshealthplan.com/providers/pdf/mng/genetic_testing_maternit.pdf. Accessed January 29, 2016.