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Directed DNA Analysis

Directed DNA analysis involves selective sequencing of relevant chromosomes. In directed DNA analysis, specific cfDNA fragments from maternal blood are used for selective sequencing. Digital analysis of selected regions (DANSR), a recently developed technique, uses directed DNA analysis and digitally analyzes sequencing results from targeted, selected genomic regions on particular chromosomes. This technique is touted as being potentially more efficient than MPSS because it uses fewer genetic fragments.