A 42-year-old male received six units of Red Blood Cells during open heart surgery six months ago. His antibody screen was negative at that time. He has returned for a follow up surgery and his antibody screen is now positive with both screen cells at the AHG phase.
(IS = Immediate Spin; AHG = Antihuman Globulin Phase; CC = Check Cells; AC = Auto Control; ND= Not done)
Refer to Case Study 1 panel below to see reactions of antibody panel.
- Reactions are occurring at the AHG phase. This indicates an IgG clinically significant antibody.
- Reactions are multiple strengths indicating either multiple antibodies or a single antibody showing dosage.
- The autocontrol is negative which indicates the patient has an alloantibody.