What primary factors tend to increase the incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant TB (XDR-TB) across the border between California and Mexico? (Choose all that apply).

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	Previous study limitations: Performing acid-fast bacillus (AFB) smears without TB culture led to an underestimation of MDR- and XDR-TB incidence.
	Cost: The amount needed for at least a 50% cure-rate for MDR- or XDR-TB totaled over $100,000.
	Patients with compromised immune systems: The reactivation of latent TB infection results from co-infection with HIV.
	Continued funding of TB clinic: Puentes de Esperanza provides a cross-border medical clinic for TB patients.
	Previous treatment for TB: Individuals previously treated for TB are four times more likely to have MDR-TB.