The page below is a sample from the LabCE course HIV: Structure, Replication, and Detection. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Infection of the Host Cell

The newly-formed double-stranded DNA molecule now migrates to the nucleus of its host cell. Once it reaches the nucleus, a viral enzyme called integrase joins the replicated HIV DNA to the host cell's DNA. The viral DNA now becomes one of the cell's chromosomes and is called a provirus. At this point, an individual is infected with and is a carrier of HIV but does not have AIDS.