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The page below is a sample from the LabCE course Pharmacology in the Clinical Lab: Therapeutic Drug Monitoring and Pharmacogenomics. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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TDM for Anticonvulsants

Anticonvulsants (also known as anti-epileptic or anti-seizure medications) typically have narrow therapeutic windows. When levels are too low, the risk for seizure is present. Drug levels that are too high can depress the central nervous system and may even lead to coma.
Examples of anticonvulsants that are monitored by TDM include:
  • Carbamazepine (Tegretol)
  • Valproic acid (Depakene)
  • Phenytoin (Dilantin)
  • Phenobarbital
  • Primidone (Mysoline)