Home Products Most Popular Contact
No items in your cart.
The page below is a sample from the LabCE course Immunohistochemistry (IHC) - Detection and Identification of Infectious Disease Processes in Surgical Pathology. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Immunohistochemistry (IHC) - Detection and Identification of Infectious Disease Processes in Surgical Pathology (online CE course) »
How to Subscribe
Histology CE Package$65 Add to cart
Individual course$20 Add to cart

Viral Markers

Deoxyribonucleic acid (DNA)
DNA viruses are usually produced in the cell nuclei. Some are enveloped and have a pleomorphic shape, such as cytomegalovirus (CMV), herpes simplex virus (HSV), and Epstein-Barr virus (EBV). Other DNA viruses are non-enveloped and have an icosahedral particle that is roughly spherical, including adenovirus (ADV), polyomavirus, human papilloma virus (HPV), and parvovirus (PARVO). Viral particles range in size from approximately 20 nm to more than 300 nm.

In some instances, replicating virus particles (inclusions) are large enough to be detected by light microscopy. Examples of DNA viruses include:

  • ADV
  • CMV
  • EBV
  • HSV
  • Varicella zoster virus (VZV)
  • Human herpes virus (HHV) 6, 7, and 8
  • HPV
  • PARVO
  • Polyomavirus
  • Poxvirus
Ribonucleic acid (RNA)
RNA viruses are most always produced in the cell cytoplasm and may be either enveloped or non-enveloped (naked). The measles virus can show in the cytoplasm. Examples of RNA viruses are:
  • Enteroviruses
  • Human immunodeficiency virus (HIV)
  • Influenza and parainfluenza
  • Measles
  • Mumps
  • Rabies
  • Rubella
  • Respiratory syncytial virus (RSV)