Acute rejection is mediated when self cells see MHC antigens or proteins after transplantation.
MHC class I antigens are found on every cell type, with the exception of red blood cells. MHC class I antigens are referred to as HLA-A, B and C.
MHC class II antigens are found on more specilized cells including dendritic cells, macrophages, B lymphocytes and vascular endothelial cells. MHC class II antigens are referred to as HLA-DR, DQ and DP.
