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Laboratory Diagnosis

  • Darkfield wet mount

- may be positive before serological tests

  • Screen with a nontreponemal test
    • Rapid plasma reagin (RPR)
    • Venereal Disease Research Laboratory (VDRL)
  • Confirm with a treponemal test
    • TP-PA
    • FTA-ABS
    • EIA/CIA

Public Health Image Library (PHIL) at CDC