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The page below is a sample from the LabCE course Vitamin D Regulation, Clinical Significance and Treatment (by ASCLS). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Vitamin D supplementation – which is better, D2 (ergocalciferol) or D3 (cholecalciferol)?

Armas, L. A. G. et al.(J Clin Endocrinol Metab 2004;89:5387-5391) have demonstrated that D3 has a considerably longer half-life than D2 and is probably preferable. However, D2 currently available in 50,000 IU doses is adequate for most patients.