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The page below is a sample from the LabCE course Sexually Transmitted Bacterial Infections (by ASCLS). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Antibiotic-Resistant Gonorrhea

  • N. gonorrhoeae has developed resistance to the antibiotic drugs prescribed to treat it:
    • Sulfonomides
    • Penicillin
    • Tetracycline
    • Ciprofloxacin
    • Ceftriaxone
  • Recommended treatment is ceftriaxone and either azithromycin or doxycycline for chlamydia with ceftriaxone in higher does
  • In 2009 23.5% of isolates were resistant to penicillin, tetracycline, ciprofloxacin, or some combination of these antibiotics
  • Decreased cephalosporin susceptibility to oral cephalosporins (cefixime) is developing
  • Extremely drug-resistant--very high minimum inhibitory concentrations
    • Azithromycin in combination with gentamicin or gemigloxacin