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The page below is a sample from the LabCE course Rh-Negative Female with Anti-D at Delivery: A Case Study. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Antigram to Explain Prior Question

The antigram below explains possible reasons for cell #2 reacting stronger:

  • The patient may have anti-D and another antibody whose corresponding antigen is on cell # 2 (eg., anti-E or anti-K).
  • The patient has an antibody other than anti-D (eg, anti-Jka) and cell #2 has a double dose of the antigen but cell #1 has only single dose.
Screen Cell Rh Rhesus Kell Duffy Kidd MNSs P Lewis Lu Results Cell
C D E c e Cw K k Kpa Fya Fyb Jka Jkb M N S s P1 Lea Leb Lua Gel
IAT
1 R1R1 + + 0 0 + 0 0 + 0 + + + + 0 + 0 + + + 0 0 1+ 1
2 R2R2 0 + + + 0 0 + + 0 0 + + 0 + + + + + 0 + 0 2+ 2
3 rr 0 0 0 + + 0 0 + 0 + 0 0 + + 0 + 0 +S 0 + 0 0 3
Auto 0 Auto