Clinically relevant information on D phenotypes can be summarized as follows:
| D phenotype | D antigen
expression | Rh(D) typing | Produce
anti-D | RBC
to transfuse | RhIg
recommended** |
| D+ | normal | direct agglutination | no | D+ or D– | no |
| Weak D | normal but weak | IAT | no | D+ or D– | no |
| Partial D | altered | direct agglutination* & IAT | yes | D– | yes |
| Partial weak D | altered & variable | direct agglutination* & IAT | yes | D– | yes |
| D– | none | IAT | yes | D– | yes |
* Depending on anti-D reagent used
** USA, UK and parts of Canada
