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The page below is a sample from the LabCE course Hemolytic Disease of the Fetus and Newborn. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Screening for Fetomaternal Hemorrhage (FMH)

Several screening methods are available to detect FMHs that require additional RhIG, including
  • Rosette method
  • Commercial fetal bleed screening tests
  • Gel agglutination fetal cell screening technique
Note: The rosette test may be falsely positive if the mother is weak-D positive and may be falsely negative if the baby is weak-D positive.
The rosette method, commonly used by many laboratories, will be briefly reviewed.