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The page below is a sample from the LabCE course Multi-drug Resistant Organisms: MRSA, VRE, and Clostridium difficile. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Molecular Methods

Molecular methods for the detection of tcd region/gene in toxigenic C. difficile are commercially available. Results can be read in as little as 2-3 hours after collection.

Molecular methods are highly sensitive and specific; initial studies suggest increased sensitivity over any other available test except culture. These methods have relatively rapid turnaround times. Although molecular methods require expensive instrumentation and personnel with the training to correctly perform the techniques, more laboratories are investigating this avenue of diagnostic testing.