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The page below is a sample from the LabCE course Theoretical and Practical Aspects of Routine H&E Staining. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Origin of Dyes: Synthetic

Synethic dyes, also known as artifical dyes, are produced from chemical transformations from organic compounds. The first synthetic or artificial dyes were made from aniline and therefore they are sometimes referred to as aniline dyes. Aniline is an organic compound derived from coal. However, all coal derivatives are not anilines. Therefore, "coal-tar dyes" is a better term to associate with artificial dyes.
Synthetic dyes significantly outnumber natural dyes.