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The page below is a sample from the LabCE course The Disappearing Antibody: A Case Study. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Antigen Phenotyping Results

The patient's pretransfusion red cells and all donor red cells involved in the case (The group O Rh-negative Red Blood Cell units that were transfused and four group O Rh-positive red cells initially crossmatched) were phenotyped for Jka.

As expected, the patient typed as Jk(a-). The six donor RBC that were incompatible in the initial crossmatch were Jk(a+).

The frequency of the Jka gene in Caucasians is ~77%, with most Caucasian red cells (50%) typing as Jk(a+b+).