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Beta Thalassemia Intermedia

Clinically, beta thalassemia intermedia is midway in severity between major and minor. Growth and development in children with this disorder can usually be considered normal and most patients have a normal life span. However, some patients can demonstrate some facial bone deformity and splenomegaly. Hemoglobin levels are usually decreased with a disproportionately high red blood cell count.

Transfusions (again with iron-chelating agents) may be used as a supportive therapy if necessary.

The genotypes associated with beta thalassmia intermedia are: B+/B+, B0/B+, or B0/B.