Clinically, beta thalassemia intermedia is midway in severity between major and minor. Growth and development in children with this disorder can usually be considered normal and most patients have a normal life span. However, some patients can demonstrate some facial bone deformity and splenomegaly. Hemoglobin levels are usually decreased with a disproportionately high red blood cell count.
Transfusions (again with iron-chelating agents) may be used as a supportive therapy if necessary.
The genotypes associated with beta thalassmia intermedia are: B+/B+, B0/B+, or B0/B.