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The page below is a sample from the LabCE course Zika Virus: Overview and Laboratory Testing. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Updated Interim Pregnancy Guidance Asymptomatic Pregnant Women with Possible Zika Virus Exposure

Overview and Testing Algorithm: Asymptomatic Pregnant Women

Overview and Testing Algorithms: Asymptomatic Pregnant Women.
The following guidelines apply to testing for asymptomatic pregnant women with possible Zika virus exposure:
  • Testing should occur three times during a pregnancy. The first testing should occur at initiation of prenatal care. (The CDC is not clear on when the other two testing should occur during pregnancy).
  • Testing should be by Zika virus NAT (serum and urine). If positive for Zika virus NAT, the woman is considered to have acute Zika virus infection.
  • If negative for Zika virus NAT, then no Zika virus RNA is detected, but Zika virus infection during pregnancy cannot be ruled out!
Note: Since Zika virus RNA declines over time and the duration of the Zika virus RNA in serum or urine can vary among pregnant women, a negative Zika virus NAT result cannot rule out a Zika virus infection.