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The page below is a sample from the LabCE course Variations in White Cell Morphology -- Granulocytes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Döhle Bodies, continued

Döhle bodies are seen in a number of conditions, including:
  • infections
  • burns
  • leukemia
  • chemotherapy
  • inflammatory states
Döhle bodies are only present when the body is responding to unusually severe stress or stimulus. This severe stress may cause the cytoplasm of some cells to mature improperly.
Their presence does not aid in the diagnosis of the disorders in which they are found, but they are frequently seen along with toxic granulation and/or vacuoles in cases of infection or burns.