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The page below is a sample from the LabCE course Variations in White Cell Morphology -- Granulocytes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Normal Band Forms vs. Pelger-Huet Bands

Recognition and diagnosis of the inherited form of Pelger-Huet anomaly is important because many of these Pelger-Huet neutrophils may be classified as bands, therefore; increased numbers of bands might be erroneously reported in these patients.

Since increased numbers bands frequently indicate infection, reporting Pelger-Huet cells as normal band forms could result in inappropriate treatment for infection. Pelger-Huet cells have denser nuclear chromatin than neutrophilic band forms.