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The page below is a sample from the LabCE course Variations in White Cell Morphology -- Granulocytes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Hypersegmented Neutrophil versus Normal Segmented Neutrophil

Another example of a hypersegmented neutrophil is noted in the top image to the right. This particular cell has six (possibly seven) lobes. Hypersegmented neutrophils are sometimes larger than normal neutrophils.
The bottom right image is one of a normal segmented neutrophil that has five lobes.