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The page below is a sample from the LabCE course Cerebrospinal Fluid. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Blast Cells

Blast cells may be seen in the spinal fluid when cell proliferation in acute leukemia or lymphoma spreads to the central nervous system. The image on the right is a stained CSF smear (1000X) containing myeloblasts. Notice the smooth chromatin pattern in the nucleus and nucleoli (indicated by the arrows).