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The page below is a sample from the LabCE course Histology Special Stains: Nervous Tissue. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Cresyl Echt Violet Staining - Diagnostic Applications

Cresyl echt violet is used to demonstrate the presence (or loss) of Nissl in neurons. The loss of Nissl substance, chromatolysis, occurs near the nucleus first and can then disappear altogether. This is an indication that neurons have been injured or damaged in some way.