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The page below is a sample from the LabCE course Basic Tissue Orientation and Paraffin Embedding Technique. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Regularly Shaped, Medium Sized Pieces

When embedding medium sized specimens with greater than one piece, locate any inked or cut surface and place all pieces facing in the same direction using these markers.
If multiple levels will be cut from the block, select the smallest mold size that will contain the pieces and still allow a border of paraffin on the outside of the specimen. This will make it easier to place more than one section on a slide during microtomy. As with other types of specimens, you will still seek to make sure all the specimens harden in the same plane so that a single representative section is easier to obtain.

Medium-sized inked pieces with inked edges facing in the same direction.