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The page below is a sample from the LabCE course Cardiac Biomarkers. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Cardiac Troponin T (cTnT)

cTnT is also encoded by a separate gene and after translation, an 11-amino acid chain is added giving this protein its cardiac specificity. Its release characteristics and elevation periods are similar to cTnI. In some AMI patients, a second increase in analyte concentration occurs. It is believed that there are two pools of cTnT, cytosolic and structurally-bound pools. The first elevation is from the cytosolic pool and the second elevation is from the structurally bound-pool released later in the necrotic process.