Clinical Manifestations of Systemic Lupus Erythematosus, continued

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The page below is a sample from the LabCE course Laboratory Evaluation of the Lupus Anticoagulant found in Antiphospholipid Syndrome (APS). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Laboratory Evaluation of the Lupus Anticoagulant found in Antiphospholipid Syndrome (APS) (online CE course)
Clinical Manifestations of Systemic Lupus Erythematosus, continued

Patients with antiphospholipid syndrome (APS) may not have SLE or present with any definable disease. By contrast, APS does occur in relation to SLE, rheumatic, or autoimmune disorders in other patients. Thrombotic events occur in up to 30% of patients with APS, with the most common events resulting in deep vein thrombosis (DVT), pulmonary embolism (PE), and cerebral arterial thrombosis. Stroke may also occur in younger individuals. One of the most serious APS complications occurs during pregnancy, resulting in recurrent spontaneous miscarriage, fetal death, or fetal developmental delay.