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The page below is a sample from the LabCE course Myelodysplastic Syndromes (MDS). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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The Significance of Auer Rods in MDS:

The presence of Auer rods in peripheral blood or bone marrow blasts is important as it would upgrade a patient's case to high grade MDS (MDS-EB-2). Refer to the image below to review the morphology of blasts containing Auer rods.
Note: If the blast count in the blood or bone marrow exceed 19%, the diagnosis is categorized as acute myeloid leukemia (AML) and not MDS.
Blast with Auer rod