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The page below is a sample from the LabCE course Overview Of Major Antigens of the Rh Blood Group System. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Four Mechanisms of Weakened Expression of the D Antigen

The following four mechanisms are responsible for weakened expression of the D antigen:
1. C in trans to RHD
2. Weak D
3. Partial D
4. Del
A discussion of each mechanism is presented in the following pages.
Harmening, DM,: Modern Blood Banking & Transfusion Practices, 6th ed. FA Davis, Philadelphia, PA, 2012, p 158-160.
Blaney, KD and Howard, PR: Basic & Applied Concepts of Blood Banking and Transfusion Practices, 3rd ed. Elsevier, St. Louis, MO, 2013, p 112-116.