As you can see in the image below, there is a cascade of biochemical reactions which takes place in order for fibrin strands to be created in secondary hemostasis. Each roman numeral below represents a specific coagulation factor of that number. These coagulation factors circulate in a non-activated form in our bloodstream at all times. When a vessel injury occurs, the factors become activated, one at a time, from the previous biochemical reaction before it.
The next slides will introduce the extrinsic, intrinsic, and common pathways, which compose the secondary hemostatic process.
