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The page below is a sample from the LabCE course Fundamentals of Hemostasis. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Consequences Linked to Deficiencies in Coagulation Factors

If coagulation factors are non-functional or are deficient, coagulation does not proceed at its usual pace; it is much slower, or even unable, to continue at all. It is critical to understand the consequences of coagulation factor deficiencies. These include:
  • Completion of the coagulation cascade (which makes fibrin) may be delayed or inhibited all together.
  • The time required for a clot to form is prolonged.
  • The vessel wall injury fails to seal and free bleeding continues.