If coagulation factors are non-functional or are deficient, coagulation does not proceed at its usual pace; it is much slower, or even unable, to continue at all. It is critical to understand the consequences of coagulation factor deficiencies. These include:
- Completion of the coagulation cascade (which makes fibrin) may be delayed or inhibited all together.
- The time required for a clot to form is prolonged.
- The vessel wall injury fails to seal and free bleeding continues.